GHK-Cu 50mg · Copper Tripeptide · Research Peptide

Compound Profile

Researcher-grade specs. No guesswork.

Each vial ships with the structural data and lot identifiers researchers need for traceable, reproducible work.

Built for the bench.

Synthesized via solid-phase peptide chemistry, purified by reverse-phase HPLC, verified by mass spectrometry, and tested for sterility and endotoxin load. Every spec below is documented on the signed Certificate of Analysis that ships with your vial.

View signed COA

Compound

GHK-Cu

Class

Copper-binding tripeptide

Sequence

Gly-His-Lys + Cu²⁺

CAS Number

49557-75-7

Molecular Formula

C₁₄H₂₄CuN₆O₄

Molecular Weight

403.9 g/mol

Concentration

50 mg / vial

Form

White powder

Purity (HPLC)

≥ 99%

Identity (LC-MS)

Confirmed

Storage

2-8°C, sealed, dry

Origin

Made in the USA

In the Literature

What researchers are studying.

A short, sourced summary of where GHK-Cu appears in the published research record. For context only. Not a claim, not a protocol, not advice.

GHK-Cu is a copper-binding tripeptide composed of glycine, histidine, and lysine (Gly-His-Lys) complexed with a copper ion. The peptide was first isolated from human plasma in 1973 and has been studied extensively for its role in copper transport and tissue-related signaling pathways.

In published preclinical literature, GHK-Cu has been investigated across cell-culture and rodent models examining its interactions with fibroblast biology, extracellular matrix proteins, copper-dependent enzymes, and inflammatory signaling cascades. Plasma concentrations of GHK have been documented to decline with age in healthy human studies, which has driven academic interest in its biology.

The compound is most-cited in the literature alongside investigations of collagen and elastin synthesis, antioxidant pathways, and copper homeostasis. It has not been approved by the FDA for any therapeutic indication and remains classified as a research compound.

For research use only. Statements above describe published research literature and do not constitute health, medical, or therapeutic claims. Not for human or veterinary use. Not evaluated by the FDA.

Documented Research Areas

Fibroblast activity and extracellular matrix research (in vitro)
Collagen and elastin synthesis pathways
Copper-binding enzyme activity (lysyl oxidase, superoxide dismutase)
Antioxidant and free-radical scavenging research
Anti-inflammatory cytokine research (TNF-α, IL-6 models)
Wound healing and ischemia models in rodent studies

Selected Studies · Peer-Reviewed Literature

A curated list of published peer-reviewed papers indexed in PubMed where GHK and GHK-Cu have been studied. Provided for research-context only. Linking to the literature does not constitute endorsement of any therapeutic application.

Pickart L, Margolina A. (2018) · Int J Mol Sci Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data PubMed · 29986520
Pickart L, et al. (2015) · Biomed Res Int GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration PubMed · 26236730
Pickart L, Margolina A. (2022) · Cosmetics The Effect of the Human Peptide GHK on Gene Expression Relevant to Anti-Aging Research PubMed · 35256962
Park JR, et al. (2016) · Biomater Res The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice PubMed · 27274846
Pickart L, et al. (2017) · Oxid Med Cell Longev GHK-Cu may Prevent Oxidative Stress in Skin by Regulating Copper and Modifying Expression of Numerous Antioxidant Genes PubMed · 28168011
Vinci C, et al. (2024) · Int J Mol Sci Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review PubMed · 38732034
Maquart FX, et al. (1988) · FEBS Lett Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu²⁺ PubMed · 3416984
Canapp SO, et al. (2003) · Vet Surg The effect of topical tripeptide-copper complex on healing of ischemic open wounds PubMed · 14648533

Transparency

Every lot. Every researcher. Same proof.

Each batch ships with a third-party Certificate of Analysis from BioRegen Analytical. HPLC purity, mass-spectrometry identity, sterility, and LAL endotoxin screening. Every test, every lot.

Your lot number ships on the label and on the COA. Enter it in the verifier any time to retrieve the original lab report.

Verify Your Batch Download Sample COA

Certificate of Analysis

BioRegen Analytical · Independent Lab · Lot #11653

CompoundGHK-Cu

CAS#49557-75-7

FormulaC₁₄H₂₄CuN₆O₄

Mol. Weight403.9 g/mol

Identity (LC-MS)PASS · 710.36 m/z

Purity (HPLC)99.72%

Retention Time3.68 min

Sterility / LALPASS

Date Tested2026-04-12

Sample · Live data on verifier

Pairs With

Related compounds.

Other research peptides in the Elixser catalog cited alongside GHK-Cu in the published research literature.

Adjacent

BPC-157

10mg · pentadecapeptide

15-amino-acid pentadecapeptide. Studied in soft-tissue, gastric mucosa, and angiogenesis research.

50/10/10mg triple-blend

Three peptides from three distinct signaling families combined in one vial.

50/10/10/10mg quad-blend

Four peptides spanning copper-binding, pentadecapeptide, anti-inflammatory tripeptide, and Tβ4-fragment research.

$125

View →

Common Questions

Answered straight.

That blue tint is the chemistry working as expected. GHK-Cu is a copper-binding tripeptide — the GHK peptide chelates a Cu²⁺ ion, and that copper coordination is what gives the lyophilized powder its characteristic light blue color. A pure white GHK-Cu powder would actually be a red flag (it would suggest the copper is not bound or that the product is just GHK without copper). The Certificate of Analysis confirms the copper-bound form by mass spectrometry.

GHK is the bare tripeptide (Gly-His-Lys). GHK-Cu is the same tripeptide bound to a copper(II) ion — the active form most documented in the published research literature. The copper coordination is what enables interactions with the copper-dependent enzymes studied in the wound healing and ECM literature. Most peer-reviewed studies on this molecule reference the Cu-bound form. This product is GHK-Cu, not bare GHK.

Every lot is tested by reverse-phase HPLC and certified at ≥99% purity. The Certificate of Analysis lists the exact lot purity (most lots run between 99.5% and 99.9%). Your COA ships with the vial and is also retrievable by lot number through our online verifier.

Testing is done by BioRegen Analytical, an independent third-party lab. Every batch goes through HPLC purity, LC-MS identity confirmation, sterility screening, and LAL endotoxin testing. The signed Certificate of Analysis ships with each vial. Same lot number, same COA, every time.

Made in the USA. Synthesized in a US cGMP-aligned facility. Tested by a US-based independent lab. Shipped from US fulfillment.

Orders ship via 2-day expedited delivery from US fulfillment. Free over $150. Vials are sealed, packaged with insulation, and shipped in tamper-evident packaging. Tracking number is sent the same day your order leaves the warehouse.

30-day money-back guarantee on every order. If a vial arrives damaged, fails to match the COA, or you change your mind within 30 days, contact us and we will refund or replace. No restocking fees, no return shipping cost on defective product.

One sealed 50mg vial of GHK-Cu as a blue-tinted powder (the copper complex gives a characteristic light blue color). Lot-stamped label. Signed Certificate of Analysis. Tamper-evident packaging. Bacteriostatic water for reconstitution research is sold separately and can be added in the cart.

Store sealed at 2-8°C, away from direct light, heat, and moisture. Sealed shelf life is 24 months from the date on the COA. Once reconstituted for research, store reconstituted material refrigerated and follow standard peptide-handling protocols for your lab.

No. All Elixser Peptides products are sold strictly for laboratory research and in vitro study. They are not drugs, food, or cosmetics. They are not for human or veterinary use, consumption, or therapeutic application. They have not been evaluated by the FDA. By purchasing, you agree to use these materials in compliance with applicable laws and ethical research standards.

Research Use Only

GHK-Cu

Researcher-grade specs. No guesswork.

Built for the bench.

What researchers are studying.

Every lot. Every researcher. Same proof.

Related compounds.

Answered straight.

Add GHK-Cu 50mg to your research arsenal.